After almost six goalless hours, the former Real Madrid man opened his account with a double to help his side to another victory.
Cristiano Ronaldo thanked his Juventus team-mates for helping him through a dry spell after he scored both goals in a 2-1 victory over Sassuolo.
The 33-year-old failed to find the net in his first three Serie A matches following a €112million transfer from Real Madrid in July before finally breaking his duck on Sunday.
He scored from close range after 50 minutes to break the deadlock and then followed up with a second 15 minutes later, angling in a drive to secure the points for Massimiliano Allegri's men.
Ronaldo ends 320-minute wait for first Juventus goal
Cristiano Ronaldo has ended a 320-minute wait for his first Juventus goal by netting against Sassuolo.
The Portuguese superstar secured a €100 million (£89m/$116m) move to Turin over the summer after opting to bring a nine-year stint with Real Madrid to a close.
He arrived in Italy as one of the most prolific marksmen of all time, but has had to be patient in a bid to open his account for the Bianconeri.