The decision to drop the England captain to the substitutes' bench failed to have a positive impact as caretaker Gareth Southgate's side were held away from home.
The Wales star made his first appearance in La Liga since returning from a hip injury to help the La Liga leaders record yet another win.
The former Southampton striker reacted badly to being substituted in his side's 1-1 draw with Spain on Thursday and will not be part of the team to face Macedonia.
The defender has no regrets over his decision to join the Serie A outfit and believes they can go far in the Champions League.
Criticism of the defender's jersey alteration in the 2-0 win over Albania has prompted him to confirm his international retirement after the Russia tournament.
The Bayern Munich star provided for his country once more during the victory over Scotland and must be considered Joachim Low's top attacking option.The dust has settled on Germany's big night in Rio and Joachim Low's rebuilding job is well under way.
The Serie A outfit struggled without their enigmatic striker in their first competitive match under their new coach.
The veteran striker broke Ronaldo's record for finals goals as Thomas Muller, Sami Khedira, Toni Kroos and Andre Schurrle combined to decimate Luiz Felipe Scolari's side.
Wilfried Bony's second-half equaliser looked set to send the Africans into the knockout phase but the striker's spot-kick in the dying seconds booked a clash with Costa Rica.
The Real Madrid star was pictured with girlfriend Irina Shayk in a racy series of pictures taken by photographer Mario Testino.